Lysosomes are the control centers for the metabolism of cells and tissues, including the brain. They break down defective proteins and other macromolecules into their basic building blocks.

For years, biomolecular condensates were thought to be simple, liquid-like droplets with little internal organization. New ...

A research team led by Sahand Jamal Rahi at EPFL’s Laboratory of the Physics of Biological Systems has introduced a new approach called “optovolution.” This technique uses light to guide the evolution ...

A new LMU study shows how proteins function reliably even without a stable 3D structure – and the crucial importance not only of short sequence motifs, but also of the chemical characteristics.

A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics.

Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic development and can positively (and less frequently, negatively) regulate gene ...

Scientists from the National University of Singapore (NUS) have developed a biochemical technique that captures fleeting ...

In the evolutionary history of life, the ability of a cell to separate its inner world from the external environment was an ...

While the PolyTAC approach, like most protein therapies, focuses on eliminating problem proteins, Shuai Gong, who earned his Ph.D. in chemistry at UMass Amherst, and Jingyi Qiu, a biomedical ...

Researchers have created nanoparticles that can remove disease-driving proteins while also delivering a chemotherapeutic or ...