A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body. It provides an ...

Single-cell RNA sequencing has transformed biology by showing which genes are active in individual cells. However, this approach requires cells to be removed from their natural environment, erasing ...

The global initiative aims to profile up to 100,000 patient specimens to scale M-Optimus, the world model of biology, representing a ~20x increase in scale over existing data available in the world ...

A single-cell atlas of brain aging epigenetics has mapped methylation, chromatin, and gene activity changes across 36 cell ...

Salk researchers create epigenetic atlas of cell type-specific changes in the aging mouse brain, representing eight different ...