Insulin-like growth factor (IGF) is a hormone that greatly influences growth in fetuses and children, but also body maintenance and metabolism in adults. IGF regulates cell proliferation, ...
We previously demonstrated that IκBα markedly increases the dissociation rate of DNA from NF-κB. The mechanism of this process remained a puzzle because no ternary complex was observed, and structures ...
Scientists determined the cryo-EM structure of IGF Ternary complex and its assembly and activation mechanism. Insulin-like growth factor (IGF) is a hormone that greatly influences growth in fetuses ...
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