Nature

MicroRNA expression profiling on arrays enhanced with locked nucleic acids

Here we describe a new array system (miRCURY TM LNA Array) for global microRNA (miRNA) profiling of biological samples. The miRCURY LNA Array system uses locked nucleic acid (LNA TM), a high-affinity ...
Nature

MicroRNA expression profiling using LNA-modified probes in a liquid-phase bead-based array

miRNAs are short, noncoding RNA molecules, 16–29 nucleotides long, that modulate gene expression by base-pairing with the 3′ untranslated region of their target mRNAs. Depending on the degree of ...